A new path to depression relief beyond medication
Why Proliv™Rx
If you’re struggling with depression that hasn’t improved with medication alone, Proliv™Rx offers a new path forward.
- A proven next-step therapy for patients who haven’t adequately improved with medication.
- Delivers treatment in privacy of home – no clinics, no waiting rooms.
- State-of-the-art brain neuromodulation therapy.
- Adjunctive therapy that enhances the effect of ongoing antidepressant treatment.
- Clinically demonstrated, meaningful improvements in depression outcomes.
- Seamlessly integrates into daily life – use while resting or watching TV.
- Physician-prescribed and monitored care.
- Safe, drug-free, and well-tolerated.
How it works
Your brain is a network of more than 80 billion neurons that communicate using tiny electrical signals. These signals share information across different regions of the brain.
In depression, communication between regions becomes disrupted, affecting mood and emotional well-being.
Proliv™Rx is designed to improve communication and connectivity across the brain. Using advanced neuromodulation, it harnesses the brain’s natural capacity to change, helping build healthier neural connections.
With its wearable headset called the NeuroRouter, Proliv™Rx delivers gentle electrical signals through electrodes (NeuroPorts) placed on the forehead and the back of the head.
Much like how a router directs signals in a network, the NeuroRouter helps guide these signals precisely and non-invasively along natural nerve pathways to key regions involved in depression.
With consistent use, Proliv™Rx may helps restore balance in your brain, so you can feel better again.
What it feels like?
Proliv™Rx therapy is designed to be comfortable and pain-free.
Most people describe the sensation as a mild tingling on the scalp.
You’re comfortable and fully aware during sessions and can resume your daily activities immediately afterward.
Proliv™Rx is portable, travel-friendly, and designed to fit easily into everyday life.
What to know
before starting
Proliv™Rx is:
- Prescription-based therapy
- Non‑invasive and designed for comfort
- Administered at home as part of a physician‑prescribed treatment
- Used alongside your regularly prescribed antidepressant medication
- Fits easily into daily routines
- Private
What your treatment
journey looks like
Based on your progress, your physician may recommend additional Proliv™Rx therapy sessions to further optimize your treatment outcome.
Does it work?
In the Proliv™Rx clinical study, 87% of patients with prior inadequate response to antidepressant medications improved by one or more depression severity levels; 56% reached mild or no depression, and 31.7% achieved full remission.
Is it safe?
- Proliv™Rx is FDA-approved and met the highest FDA requirements for safety.
- As a non-invasive therapy, Proliv™Rx has generally mild to moderate side effects.
- Throughout the therapy, data-driven reports may be shared with your prescribing physician, supporting ongoing monitoring progress and treatment plan adjustments when needed.
What leading psychiatrists are saying
Director, Center for Advanced Imaging Research & Brain Stimulation Laboratory, MUSC
Dual board-certified psychiatrist and leading researcher in neuromodulation for treatment-resistant mood disorders.
Frequently asked questions
Who is Proliv™Rx for
Adults whose depression hasn’t improved enough with at least one antidepressant medication, and are not contraindicated for the therapy, as determined by a physician.
That’s exactly who this therapy was designed for.
Proliv™Rx therapy
8 weeks, with two daily sessions (about 40 minutes each). our physician may extend it for another 8 weeks to maximise your clinical outcome.
Users usually start noticing improvement around weeks 4-6 of the therapy program.
No. You keep your current treatment unless your doctor tells you otherwise.
Most patients describe the sensation as mild tingling over the scalp. It’s designed to be comfortable.
Yes. In clinical studies, Proliv™Rx demonstrated a favorable safety profile. The majority of adverse events were mild to moderate and transient.
It’s used at home, following a prescription from your physician, who oversees your care.
Yes. Your physician reviews your progress and decides whether you should continue, extend, or adjust treatment.
No. TMS is a different technology and requires clinic visits and equipment. Proliv™Rx is an at-home therapy.
Just do the next one. Staying consistent matters, and the app helps keep you on track.
Yes. There’s no downtime.
Insurance Coverage
Coverage varies. Your doctor or care team can help you understand your options.
